FIGURE

FIGURE 1

ID

ZDB-FIG-211111-20

Publication

Qiang et al., 2021 - Fibroblast Growth Factor 21 Augments Autophagy and Reduces Apoptosis in Damaged Liver to Improve Tissue Regeneration in Zebrafish

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FIGURE 1

Fibroblast growth factor 21 improves liver regeneration after induced injury. After establishing the liver targeted-ablation model, FGF21 was administered and the treatment effect was evaluated. (A) The overall experimental process of FGF21 therapy for targeted liver ablation. (B) Liver regeneration at several time points after FGF21 treatment of the targeted ablated liver. (C) The histogram shows the quantification of the regenerated liver area assessed by ImageJ. DMSO group: without Mtz treatment, DMSO was applied. Mtz group: after Mtz treatment, the growth is natural Mtz+FGF21 group: after Mtz treatment, they were treated with FGF21 standard protein. Significance: ***p< 0.001 vs. DMSO group. Data are expressed as mean± standard error of mean (SEM) (n = 40 per group, repeat 3 times for each test). Scale bar = 250 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cq1Tg
Condition:	chemical treatment by environment: metronidazole
Observed In:	liver
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol