FIGURE

Figure 3

ID

ZDB-FIG-211029-107

Publication

Crouzier et al., 2021 - Sigma-1 Receptor Is Critical for Mitochondrial Activity and Unfolded Protein Response in Larval Zebrafish

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Figure 3

Morphological analysis of the neurons in the zebrafish retina. (A) Quantification of the number of ganglion cells, (B) quantification of the thickness of the associated layer, and (C) typical micrographs of the retina. Confocal images were obtained from section from s1r^WT and s1r^+25/+25 zebrafish retina, showing cell nuclei labeled with 4′,6-diamidino-2-phenylindole (DAPI, blue). (D) Quantification of photoreceptor cells (red and green cones) labelled with Zpr-1 antibody and (E) typical micrographs of the cones (green). (F) Quantification of rods labelled with Rho4d2 antibody and (G) typical micrographs of the rods (red). Abbreviations: GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer. Scale bars in (C,E,G) = 30 µm. The number of animals is indicated in the columns. * p < 0.05, *** p < 0.001; unpaired t-test.

Expression Data

Antibodies:	Ab5-rho zpr-1
Fish:	WT sigmar1^f19/f19
Anatomical Terms:	eye photoreceptor cell retinal rod cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sigmar1^f19/f19
Observed In:	eye photoreceptor cell retinal ganglion cell retinal ganglion cell layer retinal rod cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

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