FIGURE

FIGURE 7

ID

ZDB-FIG-210923-14

Publication

Ruggiero et al., 2021 - Period 2: A Regulator of Multiple Tissue-Specific Circadian Functions

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FIGURE 7

Per2 knockout alters the rhythmic mRNA expression of CCGs encoding key enzymes in non-essential amino acid synthesis in the adult zebrafish liver. qRT-PCR analysis of expression levels of six CCGs (A)glu1a, (B)asns, (C)gpt2l(D)glud1b(E)got1, and (F)got2a in WT and per2 KO liver tissues as described in the legend for Figure 6. A change in rhythm was observed for all genes, as determined by a significant ANOVA Genotype × Time interaction effect for all genes (p < 0.001, see Table 1). Asterisks represent levels of significance in comparing the two genotypes at each time point individually, corrected by Sidak’s method (***p < 0.001, **p < 0.01, *p < 0.05).

Expression Data

Genes:	asns glud1b glula got1 got2a
Fish:	AB per2^tlv02/tlv02 (AB)
Condition:	altered light dark cycle
Anatomical Term:	liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	per2^tlv02/tlv02 (AB)
Condition:	altered light dark cycle
Observed In:	liver
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.