FIGURE

Figure 6

ID

ZDB-FIG-210902-84

Publication

Lu et al., 2021 - Lipopolysaccharides Enhance Epithelial Hyperplasia and Tubular Adenoma in Intestine-Specific Expression of kras^V¹² in Transgenic Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Figure 6

Cotreatment with DSS and LPS exacerbated the increased number of neutrophils and macrophages in the intestines of kras+/lyz+ and kras+/mepg1+ zebrafish. (A,C) Fluorescence of neutrophils (WT/lyz+, N = 30; WT/lyz+/DSS/LPS, n = 32; kras+/lyz+, n = 31; kras+/lyz+/DSS/LPS, n = 31) or macrophages (WT/mpeg1+, N = 30; WT/mepg1+/DSS/LPS, N = 30; kras+/mpeg1+, N = 30; kras+/mepg1+/DSS/LPS, N = 30) in the intestines. (B,D) Quantification of the number of positive cells as revealed by fluorescence of neutrophils or macrophages. Differences among the variables were assessed using Student’s t-tests. Statistical significance: *** p < 0.001. Scale bar: 25 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gl23Tg nz50Tg gl23Tg; gz37Tg gz37Tg; nz50Tg
Conditions:	chemical treatment by environment: dextran sulfate sodium chemical treatment by environment: lipopolysaccharide chemical treatment by environment: mifepristone
Observed In:	gut macrophage gut neutrophil
Stage Range:	Day 4 to Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomedicines