FIGURE

Figure 5

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ZDB-FIG-210825-43
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Dray et al., 2021 - Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain
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Figure 5

NSC division events are spatiotemporally coordinated

(A) MC positions at time point t are compared, using point pattern statistics, with MC positions at other time points after fixed intervals (t+Δt), for each possible Δt (3, 6, 9, and 15 days).

(B) Left: Besag’s L functions comparing MCs with one another for all Δt intervals in Mimi (see also Figures S5A–S5E). L(obs)(r) (red lines): experimental values; L(H0,mean)(r) (black dotted lines): means under the random labeling null hypothesis; r: mean NSC cell diameter for each Dm surface: gray regions: 1-sided 95% confidence envelopes. Each fish shows a trend dispersion at Δt4. Right: combined p values for Mimi, Bibi, and Titi (Fisher’s method) (significant at Δt4).

(C and C’) Illustrations for Mimi. (C) Integrated square of the negative deviation between L(obs)(r) and L(H0, mean)(r) (surface under L(H0, mean)(r)) at Δt4. (C’) Ripley’s g function indicating an effect at the nearest neighbor’s range.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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