Figure 9
Summary of the distribution of neural progenitors in the POA. (A) Distribution of neural progenitors lining the DiV in the hypothalamus of mammals according to [17]. ?2 tanycytes with proliferative capacity express: Vim, Nestin [34], Sox2, and GFAP, while the non-proliferative tanycytes do not express GFAP. Ependymal cells are distributed in the dorsal region. (B) In zebrafish, we described a low-proliferative cell Vim+, Sox2+, and Zrf1+, and high proliferative Sox2+ cells, previously reported to express nestin [42]. Cytoplasmic Sox2/Fezf2:GFP cells were observed in the region previously shown to express cytoplasmic Sox2 [29]. (C) Cytokeratin cells are express in the ventral region of the POA in cytokeratin [43] positive ependymal-like cells similar to those seen in mammals. |