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Fig. 1

ID

ZDB-FIG-210422-32

Publication

Duong et al., 2021 - Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm

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Fig. 1

RA signaling promotes specification of posterior nkx2.5+ progenitors. (A?F) ISH for nkx2.5:Kaede (Kaede) in DMSO-treated (control) and DEAB-treated embryos at the 14s, 18s, and 20s stages (16, 18, and 19 hpf). Brackets in A and B indicate the length and width of the nkx2.5:Kaede expression. Nkx2.5 expression is expanded laterally and posteriorly and the posterior pharyngeal artery progenitors are not a distinct aggregate in RA deficient embryos. Views are dorsal with anterior up. Arrows in C and E indicate the space between the anterior nkx2.5+ and posterior nkx2.5+ aggregates. Arrows in D and F indicate the posterior limit of nkx2.5 expression and lack of posterior nkx2.5 aggregates. n ?= ?25 for all conditions examined.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 473, Duong, T.B., Holowiecki, A., Waxman, J.S., Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm, 119-129, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.