FIGURE

Fig. 1

ID

ZDB-FIG-210419-34

Publication

Wang et al., 2021 - Aquaporins Have Regional Functions in Development of Refractive Index in the Zebrafish Eye Lens

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Fig. 1

Zebrafish aqp0 mutant lens growth. Zebrafish standard length (A) and lens diameter (B) as a function of age (dpf) for WT, aqp0a−/−, aqp0b−/−, and double aqp0a−/−/aqp0b−/− mutants. WT and aqp0b−/− standard length growth plateaued at ∼24 mm after ∼350 dpf (A, red and blue); in aqp0a−/−, at ∼23 mm after ∼350 dpf (A, green). The double mutant standard length plateaued at ∼20 mm after the age of ∼180 dpf (A, black). Lens growth in WT and aqp0b−/− plateaued at ∼710 µm (B, red and blue), which corresponds to ∼500 dpf; there was no plateau for samples from aqp0a−/− mutants with a maximum attained value of 900 µm at 900 dpf (B, green), and lens growth plateaued at ∼640 µm in double homozygotes after ∼230 dpf (B, black).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mipa^{ir1090/ir1090} (AB) mipb^{ir1091/ir1091} (AB) mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)
Observed In:	lens whole organism
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.