FIGURE
Fig. 4
- ID
- ZDB-FIG-210309-4
- Publication
- Pradhan et al., 2012 - Activation of NF-kappaB prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish
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Fig. 4
FIGURE 4. Alteration of apoptotic/anti-apoptotic signaling by heat-killed E. coli treatment. Exposure of juvenile zebrafish to an intermediate concentration (5 × 106 cfu/ml) of heat-killed E. coli was performed between 15 and 35 dpf. Gonads were dissected at 35 dpf. After RNA extraction, microarray was used to evaluate apoptotic and anti-apoptotic gene expression in individual gonads. Several critical apoptotic genes were suppressed (cflar, dedd1, pycard, bnip3l, and smac), whereas anti-apoptotic (bcl2l10, aatf, api5, and mcl1a) and NF-κB-target genes (birc5a and birc5b) were up-regulated. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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Full text @ J. Biol. Chem.