FIGURE

Fig. 10

ID

ZDB-FIG-201112-13

Publication

Zhang et al., 2020 - Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish

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Fig. 10

Amh deficiency attenuated the female-to-male sex reversal in the fshr mutant. (A) Sex ratios in the amh and fshr double mutant (amh−/−;fshr−/−) at 90 and 120 dpf respectively (two different batches of fish). The number of fish analyzed is shown on top of each column. * P < 0.05; ** P < 0.01 compared to the expected sex ratio (1:1) by Chi-square test. (B) Evidence for sex reversal in the double mutant (amh−/−;fshr−/−). Two representative fish had ovotestis structure with ovarian (O) and testis (T) tissues. Note the hypotrophic ovarian tissue and hypertrophic testicular tissue in both individuals.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fshr^umo3/umo3; amh^umo17/umo17
Observed In:	gonad development male organism sex differentiation
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 517, Zhang, Z., Zhu, B., Chen, W., Ge, W., Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish, 110963, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.