ZFIN Image: Zhang et al., 2020, Fig. 10

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Figure Caption

Fig. 10 Amh deficiency attenuated the female-to-male sex reversal in the fshr mutant. (A) Sex ratios in the amh and fshr double mutant (amh−/−;fshr−/−) at 90 and 120 dpf respectively (two different batches of fish). The number of fish analyzed is shown on top of each column. * P < 0.05; ** P < 0.01 compared to the expected sex ratio (1:1) by Chi-square test. (B) Evidence for sex reversal in the double mutant (amh−/−;fshr−/−). Two representative fish had ovotestis structure with ovarian (O) and testis (T) tissues. Note the hypotrophic ovarian tissue and hypertrophic testicular tissue in both individuals.

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Phenotype details

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 517, Zhang, Z., Zhu, B., Chen, W., Ge, W., Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish, 110963, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.