FIGURE

Figure 1.

ID

ZDB-FIG-200904-18

Publication

Hu et al., 2020 - Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish

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Figure 1.

Zebrafish cq96 mutants display aberrant liver maturation. The liver was labeled by Tg(lfabp:Dendra2-NTR)^cq1. A, bright field and green fluorescence image of WT and cq96 mutant at 5 dpf showing the morphology and liver fluorescence expression. B, confocal images of WT and cq96 at 5 dpf revealing the liver size and morphology. C, whole-mount in situ hybridization (WISH) results showing the expressions of trypsin, ifabp, and cp in WT and cq96 mutant at 5 dpf. D, evaluating the liver function by WISH results of uox and gc in WT and cq96 mutant at 5 dpf. BF, bright field. Numbers indicate the proportion of larvae exhibiting the expression shown. Scale bars, 100 μm.

Expression Data

Genes:	cp Dendra2 fabp2 gc prss1 uox
Fish:	WT rbm15^cq96/cq96 cq1Tg rbm15^cq96/cq96; cq1Tg
Anatomical Terms:	exocrine pancreas hepatocyte intestine liver
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rbm15^cq96/cq96 rbm15^cq96/cq96; cq1Tg
Observed In:	hepatocyte liver whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

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