FIGURE
Fig. 1
- ID
- ZDB-FIG-200727-14
- Publication
- Sinagoga et al., 2020 - Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure
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Fig. 1
Zebrafish mitfa;tfec mutants phenocopy human colobomas. (A) At 4 dpf, mitfa−/−;tfec−/− mutants possess colobomas (outlined in red), with a range of severity (B). (C) At 48 hpf, serial sections through the distal (D) to proximal (P) axis of the CF reveal persistent expression of laminin in the mitfa−/−;tfec−/− mutant CF. The boxes indicate the areas enlarged in the insets showing laminin staining within the CF. Dorsal is upwards in all images. Scale bars: 50 µm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage Range: | Long-pec to Day 4 |
Phenotype Detail
Acknowledgments
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