FIGURE

Figure 4

ID

ZDB-FIG-200129-37

Publication

Fallata et al., 2019 - Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance

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Figure 4

The secretory signal peptide of gelatinase A orthologues is consistently and significantly less likely to be recognized than that of most other type-I secreted proteins. Violin plots of mean ‘S’ scores of the N-terminal secretory signals from orthologues of vitronectin (Vtn) and all secreted MMPs. MMPs with mean S score statistically indistinguishable from vitronectin are shown in blue. Mean S scores for orthologues of gelatinase A (red) are significantly lower than those of vitronectin and other secreted MMPs apart from MMP21 and MMP23, which undergoes type II secretion and therefore, does not have an N-terminal secretory signal. Statistically, indistinguishable groups are indicated with letters at the top of the plot, and the number of orthologues of each protein analyzed is indicated along the x-axis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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