FIGURE

Figure 7

ID

ZDB-FIG-191230-987

Publication

Liedtke et al., 2019 - ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects

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Figure 7

Investigation of TGF-beta/BMP signals in the median fin fold of fndc3a^wue1/wue1 mutants. Images show tail structures of representative control and fndc3a^wue1/wue1 mutant 22 hpf embryos stained for phosphorylated SMAD (pSMAD1/5/9) by immunofluorescence. Lack of pSMAD positive cells is observed in ventral median fin fold structures in fndc3a^wue1/wue1 mutants. All pictures display maximum intensity projections. White arrows indicate loss of pSMAD signals. Fire LUT shows pseudo-colored pSMAD1/5/9 signals. Dashed white lines indicate median fin fold borders. Scale bars: 50 µm.

Expression Data

Antibody:	Ab13-smad
Fish:	WT fndc3a^wue1/wue1
Anatomical Terms:	median fin fold ventral fin fold
Stage:	26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fndc3a^wue1/wue1
Observed In:	ventral fin fold
Stage:	26+ somites

Phenotype Detail

Acknowledgments

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