FIGURE

Fig 6

ID

ZDB-FIG-191230-640

Publication

Prill et al., 2019 - Myomesin is part of an integrity pathway that responds to sarcomere damage and disease

Other Figures

All Figure Page

Back to All Figure Page

Fig 6

Myosin and titin are required for myomesin incorporation into the sarcomere.

Embryos treated with tricaine to inhibit movement and contraction of skeletal sarcomeres from 18 to 32 hpf showed myomesin incorporates normally in untreated (A) and treated (B) wild-type siblings. Myomesin incorporation is absent in tricaine treated smyd1b^tm123a fast muscle (C; myomesin striations are visible in slow muscle (white arrowhead), D) unc45b^sb60 (E), and titin2^tg287 (F) mutant embryos.

Expression Data

Antibody:	Ab1-myom
Fish:	WT hel^tg287/tg287 smyd1b^{tm123a/tm123a} unc45b^sb60/sb60
Condition:	chemical treatment by environment: tricaine
Anatomical Terms:	skeletal muscle cell M band skeletal muscle cell sarcomere slow muscle cell M band slow muscle cell sarcomere
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hel^tg287/tg287 smyd1b^{tm123a/tm123a} unc45b^sb60/sb60
Condition:	chemical treatment by environment: tricaine
Observed In:	fast muscle cell M band fast muscle cell sarcomere sarcomerogenesis skeletal muscle cell M band skeletal muscle cell sarcomere striated muscle cell development
Stage:	Prim-15

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One