FIGURE

Fig. 7

ID

ZDB-FIG-190924-7

Publication

Albadri et al., 2019 - Redox Signaling via Lipid Peroxidation Regulates Retinal Progenitor Cell Differentiation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Catalase Endogenous Expression Was Also Required for the Switch of RPC from Proliferation to Differentiation during Normal Retinal Development

(A and B) Catalase null-mutant embryos have an increased number of proliferative cells in comparison to their wild-type siblings as observed by EdU incorporation from 2 to 3 days postfertilization (dpf). This increase was particularly striking in the region of the central retina, where by 2 dpf post-mitotic neurons are located in normal condition (GCL, ganglion cell layer; INL, inner nuclear layer; Ph, photoreceptor cell layer; and CMZ, ciliary marginal zone). Scale bars, 35 μm in (A) and (B).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cat^{ic3036/ic3036}
Observed In:	retina cell population proliferation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Cell, 50(1), Albadri, S., Naso, F., Thauvin, M., Gauron, C., Parolin, C., Duroure, K., Vougny, J., Fiori, J., Boga, C., Vriz, S., Calonghi, N., Del Bene, F., Redox Signaling via Lipid Peroxidation Regulates Retinal Progenitor Cell Differentiation, 73-89.e6, Copyright (2019) with permission from Elsevier. Full text @ Dev. Cell