FIGURE

Fig. 10

ID

ZDB-FIG-190819-8

Publication

Su et al., 2019 - A Novel AURKA Mutant-Induced Early-Onset Severe Hepatocarcinogenesis Greater than Wild-Type via Activating Different Pathways in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 10

Immunoreactive score of p-Akt immunostaining reveals that Akt is much more significantly activated in AURKA(V352I) than in AURKA(WT). (A) Representative images of p-AKT staining for PTEN in control, AURKA(WT), and AURKA(V352I) at 3, 5, 7, 9, and 11 months; (B) Selected enlarged images show the p-AKT signals from AURKA(WT)—11 M and AURKA(V352I)—11 M; (C) Statistical analysis of p-AKT immunostaining IRS score at 3, 5, 7, 9, and 11 months. The gray, orange, and blue colors represent control, AURKA(WT), and AURKA(V352I), respectively. Statistical analysis of results was performed using a two-tailed Student’s t-test. The error bar means standard deviation. Asterisks (*) represent the level of significance. * p-value ≤ 0.05; ** p-value ≤ 0.01; *** p-value ≤ 0.001.

Expression Data

Antibody:	Ab2-akt
Fish:	nn1000Tg nn1010Tg nn1011Tg
Anatomical Term:	liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nn1010Tg nn1011Tg
Observed In:	liver
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cancers