FIGURE

Fig. S5

ID

ZDB-FIG-190815-4

Publication

Cho et al., 2019 - Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish

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Fig. S5

The vascular phenotype by EGTA treatment is not affected in WT embryos. No differences were observed in the mean percentages of cerebral hemorrhage in WT embryos (A) and the mean percentages of length and branching points of CtAs (C) by 1, 10 and 100 nM EGTA treatment. (B) The compiled images of CtAs by confocal microscopy show that the development of the CtAs with dyrk1aakrb1 embryos are rescued by 1 nM and 10 nM of EGTA treatment in the Tg(kdrl:EGFP) background (see Fig. 6D). WT embryos are not affected by EGTA treatment. p-values by one-way ANOVA: n.s., not significant. Data are mean±s.e.m. Scale bar: 50 μm.

Expression Data

Gene:	GFP
Fish:	la116Tg dyrk1aa^krb1/krb1; la116Tg
Condition:	chemical treatment by environment: ethylene glycol bis(2-aminoethyl)tetraacetic acid
Anatomical Term:	central artery
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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