FIGURE

FIGURE 6

ID

ZDB-FIG-190723-805

Publication

Nelson et al., 2019 - Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord

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FIGURE 6

Glucocorticoids suppress neurogenesis. (A–C) Whole-mount preparations (lateral view) of Tg(gfap:EGFP) transgenic zebrafish show immunostaining for EGFP (green) and HuC/D (neurons, blue) along with detection of EdU (red) from 120 h post EdU incubation and sham injury (A), SCI followed by no treatment (B), and +Dex (C). Dashed boxes represent a 200-μm region centered at the lesion site used for quantifying cell counts and serve as scale bars (A is the same as B,C). (D) Quantification of the mean number of EdU-positive cells within the spinal cord (± SEM). ^∗p < 0.05; ^∗∗p < 0.01; ns, not significant; 10 whole mounts per condition.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol