FIGURE

Figure 2

ID

ZDB-FIG-190723-1576

Publication

Hong et al., 2018 - Loss-of-function of sox3 causes follicle development retardation and reduces fecundity in zebrafish

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Figure 2

Knockout of sox3 leads to follicle development retardation and a reduced fecundity in female zebrafish. (A) Schematic diagram of heterozygote incrosses. All data are from the progeny derived from heterozygote incrosses. WT, +/+; heterozygotes, +/−; homozygotes, −/−. (B) Histological analysis of adult ovaries of sox3^+/+ and sox3^−/− by H.E. staining. I, primary growth stage; II, cortical alveolus stage; III, early-vitellogenic stage; IV, late-vitellogenic stage. Scale bar, 50 μm. (C) Statistic analysis of different stages of follicles from 10 sections for each ovary of sox3^+/+and sox3^−/− (n = 3 fish per genotype). Data represent means ± SEM. T-test was performed. *P < 0.05; **P < 0.01. NS, not significant. (D) Impaired fecundity in sox3^−/−. Statistical analysis of the numbers of eggs produced by sox3^−/− incrosses or sox3^+/+ incrosses at 12-, 13- and 14-week. Data represent means ± SEM. T-test was performed. *P < 0.05

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sox3^{whu101/whu101} sox3^{whu102/whu102}
Observed In:	female organism ovarian follicle development ovarian follicle stage III ovarian follicle stage IV
Stage:	Adult

Phenotype Detail

Acknowledgments

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