ZFIN Image: Hong et al., 2018, Figure 2

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Figure Caption

Figure 2

Knockout of sox3 leads to follicle development retardation and a reduced fecundity in female zebrafish. (A) Schematic diagram of heterozygote incrosses. All data are from the progeny derived from heterozygote incrosses. WT, +/+; heterozygotes, +/−; homozygotes, −/−. (B) Histological analysis of adult ovaries of sox3^+/+ and sox3^−/− by H.E. staining. I, primary growth stage; II, cortical alveolus stage; III, early-vitellogenic stage; IV, late-vitellogenic stage. Scale bar, 50 μm. (C) Statistic analysis of different stages of follicles from 10 sections for each ovary of sox3^+/+and sox3^−/− (n = 3 fish per genotype). Data represent means ± SEM. T-test was performed. *P < 0.05; **P < 0.01. NS, not significant. (D) Impaired fecundity in sox3^−/−. Statistical analysis of the numbers of eggs produced by sox3^−/− incrosses or sox3^+/+ incrosses at 12-, 13- and 14-week. Data represent means ± SEM. T-test was performed. *P < 0.05

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Acknowledgments

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