FIGURE

Fig. 2

ID

ZDB-FIG-190715-20

Publication

Toms et al., 2019 - Phagosomal and mitochondrial alterations in RPE may contribute to KCNJ13 retinopathy

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Fig. 2

Cone photoreceptor mosaic in obe^td15 zebrafish. Optical coherence tomography was used at 3, 6 and 12 months post fertilization (mpf) to examine retinal cross-sectional views (a–f), en face cone photoreceptor mosaics (g–l) and corresponding Voronoi domain overlays (m–r) in which a Voronoi polygon is associated with each cone photoreceptor and color-coded according to the number of sides it possesses (color key shown on right). Bar charts showing the mean percentage of 3- to 10-sided Voronoi domains in wild-type (WT) and obe^td15 zebrafish at (i) 3 mpf, (ii) 6 mpf and (iii) 12 mpf (n = 5 for each age, mean ± SEM). GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; PR, photoreceptors; RPE, retinal pigment epithelium. Scale bar = 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kcnj13^td15/td15
Observed In:	retina
Stage:	Adult

Phenotype Detail

Acknowledgments

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