FIGURE

Fig. 7

ID

ZDB-FIG-181213-12

Publication

Gurung et al., 2018 - Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish

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Fig. 7

cntn2 mutants exhibit swimming deficits.

(A) Swimming assay and analysis. (B, C) Distance moved and moving duration are compared between cntn2+/− heterozygote and MZcntn2−/− mutant larvae during Lights off (B) and Lights on (C) phases. There were significant differences between cntn2+/− (n = 43) and MZcntn2−/− (n = 27). MZcntn2−/− larvae moved less than cntn2+/− siblings during both lights off (unpaired t-test, *p < 0.05) and lights on (unpaired t-test with Welch's correction, **p < 0.001) phases (B, C). MZcntn2−/− larvae also moved for shorter duration compared to cntn2+/− siblings during both lights off (unpaired t-test, *p < 0.05) and lights on (unpaired t-test, **p < 0.001) phases (B, C). Error bars show Mean ± SD.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cntn2^zou20/zou20 cntn2^zou20/+
Observed In:	swimming
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 152, Gurung, S., Asante, E., Hummel, D., Williams, A., Feldman-Schultz, O., Halloran, M.C., Sittaramane, V., Chandrasekhar, A., Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish, 1-12, Copyright (2018) with permission from Elsevier. Full text @ Mech. Dev.