FIGURE
Fig. S12
- ID
- ZDB-FIG-181206-13
- Publication
- Ahlberg et al., 2018 - Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
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Fig. S12
Sarcomere TEM images larval stage TEM images from 3 dpf ttn.2sfc9+/+ (a-b) and ttn2.sfc9+/- (c-d) larvae hearts. a) show well-defined sarcomeres, with distinguishable Z-discs with adjacent I-bands, and distinct M-lines throughout the cardiac tissue. Scale bar 2μM (a)and 4 μM (b). In heterozygous mutant larvae (c) the sarcomere structure is less organised. The z-discs appear blurred and the I-bands are absent (d) Scale bar 2μM (c) and 4 μM respectively(d) |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
Acknowledgments
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Full text @ Nat. Commun.