FIGURE

Fig. 5

ID

ZDB-FIG-181120-14

Publication

Sarangdhar et al., 2018 - Parentally inherited long non-coding RNA Cyrano is involved in zebrafish neurodevelopment

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Fig. 5

Ectopic over-expression of miR-7 leads to defective ventricle opening and it is rescued by Cyrano. First panel shows control mimic injected zebrafish embryos, second panel with 300 pg of miR-7 mimic injected embryos, third panel has embryos injected with 6 pg of Cyrano transcript and 300 pg of miR-7 mimic and fourth panel has embryos injected with 6 pg of miR-7 resistant Cyrano transcript (miR-7 res Cyrano) along with 300 pg of miR-7 mimic imaged at 24 hpf. Defects were observed (shown by dotted arrow) in 70 out of 124 animals with miR-7 mimic injection and these defects were restricted to 5 out of 23 and 13 out of 48 animals after rescue with wild type Cyrano or miR-7 res Cyrano, respectively. Forebrain (F), Midbrain (M), Hindbrain (H) ventricles shown by dotted lines.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nucleic Acids Res.