FIGURE

Fig. 1

ID

ZDB-FIG-180924-27

Publication

López-Muñoz et al., 2018 - An Adult Zebrafish Model Reveals that Mucormycosis Induces Apoptosis of Infected Macrophages

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

M. circinelloides R7B is highly pathogenic for zebrafish. Zebrafish were i.p. injected with 2.5 × 10⁵ or 10⁷ (high dose: HD) live or UV-killed sporangiospores of the R7B or NRRL strains. (A) The survival rates of infected zebrafish are shown. Each experimental group contained 20 zebrafish, and each experiment was performed in duplicate. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001. (B) Gross morphological examinations of adult zebrafish infected with M. circinelloides R7B and NRRL were imaged at 16 hpi. (C) Histological analysis of M circinelloides-infected zebrafish. Transverse sections were obtained from zebrafish injected with 2.5 × 10⁵ R7B spores/fish or 10⁷ NRRL spores/fish at 16 hpi. Note that the mycelium (black arrows) can invade several organs and promotes a strong leukocyte infiltration (red arrows). L, liver; G, gut; M, muscle; O, ovary; T, testis. Scale bars 10 µm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	fungal treatment by injection: Mucor circinelloides
Observed In:	gut intestine leukocyte muscle ovary testis whole organism
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.