FIGURE
Fig. S7
- ID
- ZDB-FIG-180914-32
- Publication
- Soma et al., 2018 - Elesclomol restores mitochondrial function in genetic models of copper deficiency
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Fig. S7
ES supplementation rescues pigmentation of Ctr1 knockout zebrafish while equivalent concentration of copper fails to rescue this defect. (A) Clutches of embryos from a WT zebrafish and (B) from a cross of a pair of Ctr1+/- heterozygous zebrafish were imaged at 48hpf following treatment with and without 100 nM elesclomol (ES) or 100 nM copper chloride (CuCl2). Arrowheads in (B) indicate homozygous Ctr1-/- embryos with a pigmentation defect. Notably, not a single embryo with pigmentation defect was observed upon ES treatment. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
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| Conditions: | |
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| Stage: | Long-pec |
Phenotype Detail
Acknowledgments
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Full text @ Proc. Natl. Acad. Sci. USA