FIGURE

Fig. 4

ID

ZDB-FIG-180829-18

Publication

Luo et al., 2015 - Tanshinol stimulates bone formation and attenuates dexamethasone-induced inhibition of osteogenesis in larval zebrafish

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Fig. 4

Effects of tanshinol on osteoblasts differentiation in tg(sp7:egfp) zebrafish larvae. Fluorescence images of (A) the dorsal aspect measured using laser scanning confocal microscopy in tg(sp7:egfp) zebrafish larvae at 9 days' postfertilisation (dpf) with or without tanshinol (0.5μM, 1μM, 2.5μM, 5μM). (B) Effect of tanshinol on green fluorescence area of 9-dpf tg (sp7:egfp) zebrafish. (C) Effect of tanshinol on green fluorescence integral optical density of 9-dpf tg (sp7:egfp) zebrafish. Con = control, egg water; IOD = integral optical density; T_0.5 = tanshinol 0.5μM; T₁ = tanshinol 1μM; T_2.5 = tanshinol 2.5μM; T₅ = tanshinol 5μM. Data are given as mean ± standard deviation (n ≥ 9). ^∗p < 0.05 versus vehicle control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	b1212Tg/b1212Tg
Condition:	chemical treatment by environment: plant metabolite
Observed In:	cranium bone mineralization osteoblast differentiation
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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