FIGURE

Fig. S2

ID

ZDB-FIG-180427-30

Publication

Hui et al., 2017 - Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs

Other Figures

All Figure Page

Back to All Figure Page

Fig. S2

Survival gene expression and apoptosis in injured zT_reg cell depleted tissues, Related to Figure 5. (A–C) qRT-PCR analysis of survival factors in injured spinal cords (A), hearts (B), and retinas (C) from control and zT_reg cell-depleted fish (mean ± SEM, n = 6). (D–F) Immunofluorescence for activated Caspase-3. Arrows indicates apoptotic neurons (D; HuC/D⁺Caspase- 3⁺), cardiomyocytes (E; MHC⁺Caspase-3⁺), and Müller glia (F; gfap:GFP⁺Caspase-3⁺). Images show the rostral stump of a 7-dpi spinal cord. cc, central canal; epi, injury epicenter. Dotted line, wound border plane. (G–I) Quantification of D–F (mean ± SEM, n = 5). Mann–Whitney U test. NS, not significant. Scale bars, 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Cell, 43, Hui, S.P., Sheng, D.Z., Sugimoto, K., Gonzalez-Rajal, A., Nakagawa, S., Hesselson, D., Kikuchi, K., Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs, 659-672.e5, Copyright (2017) with permission from Elsevier. Full text @ Dev. Cell