FIGURE

Fig. 1

ID

ZDB-FIG-180426-5

Publication

McGurk et al., 2017 - In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Homozygous carriers of b1024 display second pharyngeal arch lower jaw muscle defects. (A) Schematic of connective tissues in the larval zebrafish jaw, modified from Chen and Galloway, 2014. (B, C) Ventral craniofacial muscles in wild-type and b1024 embryos. (C) Muscle fibers from an intermandibularis posterior muscle extend past the mandibulohyoid junction and insert alongside the adjacent interhyal muscle or at the hyohyal junction (arrows). Muscle fibers apparently from the sternohyoideus are present in the ventral midline of mutants (arrowhead). Ectopic muscle fibers split off from the intermandibularis anterior muscle in a small percentage of mutants (asterisk). (D) 4x digital zoom of a single Z slice from confocal image in C. Arrows show ectopic paths of intermandibularis posterior muscle fibers. Arrowheads show ectopic midline attachments of interhyal muscle fibers. A three-way junction (red arrowhead in D) forms between ectopic intermandibularis posterior, interhyal, and hyohyal (asterisk in D) muscle fibers. All images ventral view, anterior to the left. Scale bars = 50 μm

Expression Data

Gene:	mCherry
Fish:	au101Tg; y1Tg cyp26b1^b1024/b1024; au101Tg; y1Tg
Anatomical Terms:	adductor mandibulae hyohyoideus interhyoideus sternohyoid ventral intermandibularis anterior ventral intermandibularis posterior
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cyp26b1^b1024/b1024; au101Tg; y1Tg
Observed In:	hyohyoideus skeletal muscle cell interhyoideus determination of muscle attachment site sternohyoid skeletal muscle cell ventral intermandibularis anterior skeletal muscle cell ventral intermandibularis posterior ventral intermandibularis posterior determination of muscle attachment site ventral intermandibularis posterior skeletal muscle cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.