FIGURE

Fig. 5

ID

ZDB-FIG-171227-43

Publication

Pimtong et al., 2014 - Drl.3 governs primitive hematopoiesis in zebrafish

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Fig. 5

L3MO-induced defects are due to knockdown of drl.3 activity.

(a) WISH of gata1a at 24 hpf, l-plastin at 25 hpf, and slc4a1a at 48 hpf in L3MM- and L3MO-injected embryos and embryos co-injected with L3MO and drl.3 mRNA. Embryos shown as lateral views, head left. WISH for l-plastin also shows dorsal, anterior views. (b) Percent of L3MM- and L3MO-injected and L3MO/drl.3 mRNA co-injected embryos with normal (wt) or decreased (*; estimated ≤ 60% of normal) numbers of gata1a or slc4a1a-expressing cells. The numbers of embryos are indicated in the columns. ***P < 0.0001 (Fisher's exact test). (c) Percent of embryos with normal (wt) or decreased (*) numbers of l-plastin-expressing cells, as labeled. The numbers of embryos are indicated in the columns. *P = 0.0445 (Fisher's exact test).

Expression Data

Genes:	gata1a lcp1 slc4a1a
Fish:	AB AB + MO1-drll.3
Knockdown Reagent:	MO1-drll.3
Anatomical Terms:	erythroid lineage cell monocyte
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-drll.3
Knockdown Reagent:	MO1-drll.3
Observed In:	erythroid lineage cell monocyte
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

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