Fig. 3
- ID
- ZDB-FIG-171113-31
- Publication
- Powell et al., 2016 - Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons
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Injury paradigms stimulate regenerative response signatures that exhibit both commonality and uniqueness. Fish were given an intraperitoneal injection of BrdU at 2 dpi and then sacrificed at 2 dpi (3 hours post BrdU injection), 4, 7, 14 and 30 dpi. (A?C) BrdU+ nuclei were counted and the percentage of BrdU+ nuclei residing in the (A) ONL, (B) INL and (C) GCL was determined for individual samples for each injury model. Data represents means?±?s.d. (n???3). *P?<?0.04549. (D?I) Representative images of retinal sections analyzed in (A?C) that were immunostained for BrdU at (D?F) 2 dpi or (G?I) 30 dpi following (D,G) needle poke, (E,H) PA or (F?I) NMDA injury. Scale bar is equal to 50??m. Abbreviations are as in Fig. 1. |