Fig. 3
- ID
- ZDB-FIG-171018-12
- Publication
- Leerberg et al., 2017 - Fibroblast growth factor signaling is required for early somatic gonad development in zebrafish
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fgf24 is expressed in somatic gonad cells during wild-type larval development. (A, B, C, D, E) Single plane confocal micrographs of whole-mount larval gonads after fluorescent in situ hybridization detecting fgf24 (red). At 5 dpf, fgf24 is not detected by fluorescent in situ hybridization (A). By 8 dpf, fgf24 is detected in SGCs (B) and is restricted to an outer layer of SGCs at 10 (C) and 16 (D) dpf. By 20 dpf, expression is primarily restricted to SGCs on the dorsal edge of the gonad (E). (A', B', C', D', E') Gonads dissected from fgf24 mutants age-matched to the wild-type animals depicted in A, B, C, D, and E. Gonads are outlined with white dotted lines. A-E' are sagittal optical sections where anterior is to the left and dorsal is up. Nuclei labeled with DAPI (blue), germ cells labeled with Vasa (green). Scale bars = 20 μm. |
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Stage Range: | Day 5 to Days 14-20 |