FIGURE
Fig. S1
- ID
- ZDB-FIG-170914-29
- Publication
- Scott et al., 2017 - Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein
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Fig. S1
BBS6 knockout HEK 293T and IMCD3 cell lines and zebrafish bbs6 knockdown. Alignments showing the indels generated by CRISPR/Cas9 in mIMCD-3 cells (A) and HEK 293T cells. Alignment shows reference genome, wildtype control, generated mutant line, and guide(s) used for targeting (B). Cilia lengths were measured in control (C), bbs6 morphants (D), morphants with overexpression of BBS6 (E), or BBS6H84Y; A242S (F). Box and whisker plot representing the 5–95 percentiles of the collected data; n = 128–288 per group (G). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage Range: | 5-9 somites to 10-13 somites |
Phenotype Detail
Acknowledgments
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