FIGURE

Fig. 4

ID

ZDB-FIG-170829-3

Publication

Abrial et al., 2017 - TGF-? Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation

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Fig. 4

TGF-? Pathway Components Are Expressed in the Pharynx during PAA Angioblast Differentiation

(A?L) Left lateral views of indicated TGF-? pathway component expression in 28 hr post-fertilization (hpf) embryos. (A-D) Transcripts encoding the canonical TGF-? receptor paralogs RIa/b and RIIa/b are broadly distributed in the pharyngeal region. (E?G, I, and J) Expression of the indicated TGF-? ligands in the pharynx. (H, K, and L) Double in situ hybridization highlighting overlap of indicated TGF-? pathway component transcripts with transcripts encoding the pharyngeal endodermal pouch marker, nkx2.3. (n = 30?40 embryos per in situ hybridization probe). Scale bars, 200 ?m.

Expression Data

Genes:	ltbp3 nkx2.3 tgfb1a tgfb1b tgfb2 tgfb5 tgfb3 tgfbr1a tgfbr1b tgfbr2a tgfbr2b
Fish:	WT
Anatomical Terms:	pharyngeal arch pharyngeal arch anatomical region pharyngeal pouch 1 pharyngeal pouch 2 pharyngeal pouch 3 pharynx
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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