FIGURE

Fig. S5

ID

ZDB-FIG-161221-33

Publication

Mahalwar et al., 2016 - Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish

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Fig. S5

Interactions between xanthophores and the other pigment cells. (A) Bright field of time lapse recordings of melanophores and DsRed labeled xanthophores during metamorphosis (corresponding to Fig. 6). (A1'-3') wild type, (B1'-3') shady and (C1'-3') homozygous leo^tK3 mutant xanthophores (inside white dotted circles) retract their protrusions to give space to the newly arriving melanophores. (D) Cartoon representation of proposed cellular interactions. The communication between xanthophores and iridophores is mediated by connexins41.8 and 39.4. The melanophore-xanthophore communication is a multi-step process, initially xanthophores react to incoming melanophores independently of the known connexins, however, later steps are dependent on Cx41.8 and Cx39.4.

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Acknowledgments

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