FIGURE

Fig. 1

ID

ZDB-FIG-160729-4

Publication

Lv et al., 2016 - Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels

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Fig. 1

Ribeye and Synaptic Ribbons Remain in the Retina of ribeye a(Δ10)/ ribeye b(Δ7) (re[a(Δ10)/b(Δ7)]) double homozygous mutants.

(A) Confocal image of Ribeye b (green) and post-synaptic maker MAGUK (red) staining in 5-dpf re[a(Δ10)/b(Δ7)] homozygous mutants. DAPI (blue) stains for the nucleus. Scale bar, 5 µm.

(B) 3× magnification of outer plexiform layer staining in 5-dpf re[a(Δ10)/b(Δ7)] homozygous mutants retina. Scale bar, 5 µm.

(C) 3× magnification of inner plexiform layer staining in 5-dpf re[a(Δ10)/b(Δ7)] homozygous mutants retina. Scale bar, 5 µm.

(D) Electron micrograph of photoreceptor ribbon from 5-dpf re[a(Δ10)/b(Δ7)] homozygous mutant retina. Scale bar, 200 nm.

Expression Data

Gene:	ctbp2l
Antibodies:	Ab1-pan-MAGUK Ab2-ctbp2l
Fish:	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401
Anatomical Terms:	retinal inner plexiform layer postsynapse retinal outer plexiform layer retinal outer plexiform layer postsynapse
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401
Observed In:	retinal outer plexiform layer ribbon synapse
Stage:	Day 5

Phenotype Detail

Acknowledgments

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