FIGURE

Fig. 7

ID

ZDB-FIG-160726-14

Publication

Housley et al., 2016 - Cavin4b/Murcb Is Required for Skeletal Muscle Development and Function in Zebrafish

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Fig. 7

Caveolin expression and growth factor signaling in Cavin4b/Murcb deficient zebrafish. A. Representative confocal micrographs of Cav1 and Cav3 immunostaining of 10 µm transverse sections prepared from the trunk of 10 wpf murcb^s983/+ and murcb^s983/s983 zebrafish. B. Representative confocal micrographs of Cav1 whole mount immunostaining in murcb^s983/+ and murcb^s983/s983 zebrafish at 80 hpf. Mean relative fluorescence profiles from at least 6 larvae for each genotype. Pixel intensity was measured across a 3 µm segment covering a single striation and plotted relative to the background intensity between stria. SEM is represented by thin lines. C. Immunoblot of phospho-Thr202/Tyr204-Erk1/2 and total Erk1/2 from skeletal muscle prepared from 3 murcb^s983/+ and 3 murcb^s983/s983 10 wpf zebrafish.

Expression Data

Antibodies:	Ab1-cav1 Ab1-cav3 Ab9-mapk Ab13-mapk
Fish:	WT cavin4b^s983/s983 cavin4b^s983/+
Anatomical Terms:	skeletal muscle skeletal muscle cell cytoplasm skeletal muscle cell sarcolemma skeletal muscle cell sarcomere
Stage Range:	Protruding-mouth to Days 45-89

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cavin4b^s983/s983
Observed In:	skeletal muscle skeletal muscle ERK1 and ERK2 cascade skeletal muscle cell cytoplasm skeletal muscle cell sarcomere
Stage Range:	Protruding-mouth to Days 45-89

Phenotype Detail

Acknowledgments

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