FIGURE
Fig. 7
- ID
- ZDB-FIG-160428-15
- Publication
- Sallin et al., 2016 - Acute stress is detrimental to heart regeneration in zebrafish
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Fig. 7
Inhibition of IGF signalling impairs CM proliferation. (a-d) Sections of cmlc2::DsRed2-Nuc (red) hearts at 7 dpci reveal that the treatment with 5 µM NVP-ADW742 (inhibitor of Igf1r) significantly reduces p-Igf1r levels (a,b, green) and MCM5-positive CMs (c,d, green). (e-f) Quantification of p-Igf1r (e, N ≥ 4) and the number of proliferating CMs (f, N ≥ 10) in the whole ventricles at 7 dpci. **p < 0.01, ***p < 0.001. Dashed lines encircle the cryoinjured areas. Scale bars, 100 µm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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