FIGURE
Fig. 2
- ID
- ZDB-FIG-160412-13
- Publication
- Wan et al., 2016 - Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia
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Fig. 2
RPL5 is required for both primitive hematopoiesis and definitive hematopoiesis, which are partially mediated the by P53 pathway in zebrafish. a-c The expression of scl was significantly decreased in RPL5 MO zebrafish and was partly rescued in RPL5 and P53 double MO zebrafish at 12 hpf. d-i The expression of gata1 and pu1 was significantly decreased in RPL5 MO zebrafish and was partly rescued in RPL5 and P53 double MO zebrafish at 12 hpf. j-o The expression of c-myb and runx1 was significantly decreased in RPL5 MO zebrafish and was partly rescued in RPL5 and P53 double MO zebrafish at 48 hpf |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Knockdown Reagents: | |
| Anatomical Terms: | |
| Stage Range: | 5-9 somites to Long-pec |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagents: | |
| Observed In: | |
| Stage Range: | 5-9 somites to Long-pec |
Phenotype Detail
Acknowledgments
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Full text @ BMC Med. Genomics