FIGURE

Fig. 5

ID

ZDB-FIG-160323-15

Publication

Lin et al., 2015 - Ras-Related Nuclear Protein is required for late developmental stages of retinal cells in zebrafish eyes

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Fig. 5

Ran deficiency impaired eye cell differentiation. (A-R) Temporal dynamics of the expression of cell differentiation marker (A-F) p57kip2, (G-L) deltaC and (M-R) ath5 on the eyes of WT and ran-deficient embryos. (S, T) Expression of cell differentiation marker neuroD on the eyes of WT and ran-deficient embryos. (U-X) Expression of the cell differentiation marker (U,V) HuC/D protein and (W,X) Neurolin protein on the eyes of WT and ran-deficient embryos. (A-F) Dorsal view with anterior to the top; (G-T) lateral view with anterior to the left; (U-X) dorsal view with anterior to the top, and only the left eyes are presented to show better detail. AL, amacrine layer; CMZ, ciliary marginal zone; GCL, ganglion cell layer; ONL, outer nuclear layer. All images are representative of at least three repeats with n>25 for each repeat.

Expression Data

Genes:	atoh7 cdkn1ca dlc neurod1
Antibody:	zn-8
Fish:	AB AB + MO1-ran
Knockdown Reagent:	MO1-ran
Anatomical Terms:	amacrine cell ciliary marginal zone eye retinal ganglion cell layer retinal outer nuclear layer
Stage Range:	Prim-5 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-ran
Knockdown Reagent:	MO1-ran
Observed In:	ciliary marginal zone eye retinal ganglion cell layer
Stage Range:	Prim-5 to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Dev. Biol.