FIGURE

Fig. S1

ID
ZDB-FIG-160317-24
Publication
Sempou et al., 2016 - Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo
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Fig. S1

Recovery of epiboly in PrP-1 morphants by treatment with degradation and endocytosis inhibitors. A. Treatment of PrP-1 morphants with DMSO alone does not restore epiboly. B. Treatment with protein degradation inhibitors restores AJ components at the plasma membrane of PrP-1 morphants (only MG-132 shown). Immunofluorescence (IF) analysis of E-cadherin and β-catenin in the deep cell layer of 6 hpf embryos. Scale bar = 10 µM.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Neurodegener.