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Fig. S1
Recovery of epiboly in PrP-1 morphants by treatment with degradation and endocytosis inhibitors. A. Treatment of PrP-1 morphants with DMSO alone does not restore epiboly. B. Treatment with protein degradation inhibitors restores AJ components at the plasma membrane of PrP-1 morphants (only MG-132 shown). Immunofluorescence (IF) analysis of E-cadherin and β-catenin in the deep cell layer of 6 hpf embryos. Scale bar = 10 µM.
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Full text @ Mol. Neurodegener.