FIGURE

Fig. 5

ID

ZDB-FIG-160315-21

Publication

Govindan et al., 2016 - Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration

Other Figures

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Fig. 5

Morpholino mediated knockdown of hapln1a results in reduced Acan protein levels.

Longitudinal section of fin rays treated with hapln1a control morpholino (Hapln1a MM) and hapln1a targeting morpholino (Hapln1a MO). Immuno-staining for Acan (blue) and counterstained for nuclei with Propidium Iodide (PI, red). Compared to the control Hapln1a MM treated fins, Hapln1a MO treated fins show reduced staining for Acan. Arrow identifies the basal layer of epithelium; arrow head identifies the bone; m, mesenchyme; e, epithelium. Arrow identifies the basal layer of epithelium; arrow head identifies the bone; m, mesenchyme; e, epithelium. Scale bar represents 20 µm.

Expression Data

Gene:	acanb
Antibody:	Ab1-acan
Fish:	AB/C32 AB/C32 + MO2-hapln1a
Condition:	amputation: caudal fin
Knockdown Reagent:	MO2-hapln1a
Anatomical Term:	regenerating fin
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB/C32 + MO2-hapln1a
Condition:	amputation: caudal fin
Knockdown Reagent:	MO2-hapln1a
Observed In:	regenerating fin
Stage:	Adult

Phenotype Detail

Acknowledgments

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