FIGURE

Fig. 6

ID

ZDB-FIG-160208-15

Publication

Pinto et al., 2016 - Lxr regulates lipid metabolic and visual perception pathways during zebrafish development

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Fig. 6

Apoptosis and morphological alterations in the eyes of Lxr ligand-treated or Lxr morpholino injected zebrafish larvae. Number of acridine orange stained spots in eyes of 4 dpf zebrafish larvae treated with T0 and GW (A). TUNEL staining of eye sections of zebrafish larvae treated vehicle only (B), T0 (C) or GW (D), Hematoxylin and eosin staining of eye sections of control morpholino (E) and Lxr morpholino (F) zebrafish larvae at 4 dpf. Representative images are shown. IPL; inner plexiform layer (Scale bars 50 µm). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment by environment: liver X receptor agonist
Observed In:	eye eye apoptotic process retinal inner plexiform layer
Stage:	Day 4

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 419, Pinto, C.L., Kalasekar, S.M., McCollum, C.W., Riu, A., Jonsson, P., Lopez, J., Swindell, E., Bouhlatouf, A., Balaguer, P., Bondesson, M., Gustafsson, J.Å., Lxr regulates lipid metabolic and visual perception pathways during zebrafish development, 29-43, Copyright (2016) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.