FIGURE
Fig. S5
- ID
- ZDB-FIG-150921-36
- Publication
- Anderson et al., 2015 - In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress
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Fig. S5
Glomerular ultrastructure of apol1 morphants complemented with human risk alleles. Transmission electron microscopy of zebrafish larval glomeruli imaged at 5 dpf. (A, B) apol1 morphants complemented with risk alleles, G1 and G2 do not rescue the observed defects caused by apol1 suppression, with naked patches of glomerular basement membrane and microvillus processes apparent. *, microvillus protrusions; filled arrowheads, glomerular basement membrane. Scale bars, 500nm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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