FIGURE

Fig. S2

ID

ZDB-FIG-150915-32

Publication

Willems et al., 2015 - The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish

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Fig. S2

lrp5 CRISPR2 injected embryos display normal induction of CNCCs, but show defects in the craniofacial skeleton.

(A-D) foxd3 expression at 10 ss in wild-type embryos (A,B) and lrp5 CRISPR2 injected embryos (n = 20/20 with normal foxd3 expression; C, D). (A,C) are lateral views with anterior to the left, (B,D) are dorsal views. (E-H) Additional examples for embryos with varying degrees of cartilage defects (class I, F; class II, G; class III, H). Combined bone and cartilage staining at 7 dpf of wild-type (E) and lrp5 CRISPR1+2 injected embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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