FIGURE

Fig. 4

ID

ZDB-FIG-150810-12

Publication

Evason et al., 2015 - Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

Other Figures

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Fig. 4

JNK inhibitors suppress larval liver enlargement caused by activated β-catenin.

(A) Brightfield images of control sibling and transgenic 6-day-old fixed larvae, treated with DMSO or JNK inhibitors. Livers are outlined. Scale bar, 100 µm. (B-C) Graphs showing average liver size ± SEM of 6-day-old control sibling and transgenic larvae treated for 3 days with SP600125 (B) or EMD 420123 (C) at the indicated dosages. N values are shown above the x-axis. Asterisks indicate p-values for 2-way ANOVA comparing drug-treated zebrafish to DMSO-treated siblings with the same genotype: *, p<0.05; ***, p<0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	as3Tg; s704Tg
Observed In:	liver
Stage:	Day 6

Phenotype Detail

Acknowledgments

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