FIGURE

Fig. 2

ID

ZDB-FIG-150430-4

Publication

Moritz et al., 2015 - Live imaging reveals a new role for the sigma-1 (σ1) receptor in allowing microglia to leave brain injuries

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Fig. 2

Treatment with σ₁ agonist does not lead to a clearance phenotype.

(A) Acridine orange staining of 3,5 dpf zebrafish larvae treated with DMSO. (B) Acridine orange staining of 3,5 dpf zebrafish larvae treated with DTG. (C) Acridine orange staining of 3,5 dpf zebrafish larvae treated with PB190. (D) Quantification of uncollected acridine orange positive cells in a 3,5 dpf larvae treated with DMSO, DTG or PB190. Scalebar for all images 20 µm. All images were obtained using an Andor Spinning Disk Confocal with a 20x/NA0.7 objective. Statistical analysis was performed using a Kruskal-Wallis test with a Dunn’s multiple comparison test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment: agonist, physical alteration: brain
Observed In:	glial cell apoptotic cell clearance
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neurosci. Lett.